Neo Gen Screening and Cambridge Isotope Laboratories have recently produced stable isotope internal standards to meet your needs in the tandem mass spectrometry applications in newborn screening of acylcarnitines and amino acids metabolites. Twenty of the highest quality acylcarnitine and amino acid standards are synthesized and validated for exceptional purity and accurate enrichments. These standards are available in either of 2 kits containing 10 vials of dry standard prepared from premixed, certified solutions of L-amino acids (kit A) or L-carnitine and acylcarnitines (kit B). Our standards are designed to help insure the most accurate analysis of important diagnostic markers in screening today.
- Each vial, when reconstituted, contains certified concentrations of high purity stable isotope labeled internal standards.
- Using published sample preparation methods (see references below), each kit will provide enough standards for preparation of approximately 10,000 blood spots when using a single 3/16" diameter punch.
Blood volume from the excised spots is the determinant of i.s. consumption rate, ie 5,000 samples can be prepared using two 3/16" diameter punches 15.2 uL whole blood, 10,000 samples can be prepared using one 3/16" diameter blood punch 7.6 uL on S&S 903 Filter Paper.
- Each vial and kit is color coded to reduce the possibility of error.
- Each kit can be used individually for selective screening or in combination for comprehensive screening.
- References:
Clin Chem 1993, 39:66-71, Clin Chem 1995, 41:62-68, Clin Chem 1996,42:349-55, Clin Chem 1997,43:2106-2113
15N13C-glycine 2H4-alanine 2H8-valine 2H3-leucine 2H3-methionine 2H5-phenylalanine 2H4-tyrosine 2H3-aspartate 2H3-glutamate 2H2-ornithine 2H2-citrulline 2H413C-arginine
2H9-L-carnitine 2H3-acetylcarnitine 2H3-propionylcarnitine 2H3-butyrylcarnitine 2H9-isovalerylcarnitine 2H3-octanoylcarnitine 2H9-myristoylcarnitine 2H3-palmitoylcarnitine
| Not Available in the United States pending FDA approval |
Send Inquiries and Orders to:
Donald H. Chace, Ph.D.
Director of Mass Spectrometry
Neo Gen Screening
Phone: Fax:
email:
| Item | Description | Unit Price |
|---|---|---|
| NGS-KitA | Amino Acid Kit A | $ 1,950.00 |
| NGS-KitB | Acylcarnitine Kit B | $ 1,950.00 |
| *NGS-VLA | 1 ml Vial from Kit A | $ 300.00 |
| *NGS-VLB | 1 ml Vial from Kit B | $ 300.00 |
| **NGS-KAB | Dual Kit A and Kit B | $ 3510.00 |
| * limited quantities only | ||
All kits (A and B) are sold individually.
Individual vials are not sold separately except by
special arrangement or evaluation**Price reflects a 10% discount when ordering Dual Kit A and Kit B
Not Available in the US pending FDA approval.
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